Structural Formula

Physical Properties
Appearance: white crystalline powder
Density: 1.159
Melting point: 78-80 °C(lit.)
Boiling point: 221 °C(lit.)
Refractivity: 1.4274
Flash point: 220-222 °C
Solubility: Soluble in liquid ammonia, aliphatic amines, water, alcohols, pyridine, chloroform, glycerol, hot benzene, butanone, butanol, benzyl alcohol, cyclohexanone, isoamyl alcohol, etc., slightly soluble in benzene, insoluble in ether. It is well soluble in most inorganic salts.

Safety Data
General

Application
 Used as a plasticizer and an industrial solvent.Acetamide has uses in electrochemistry and the organic synthesis of pharmaceuticals, pesticides, and antioxidants for plastics. It is a precursor to thioacetamide.

Acetamide has a high dielectric constant and is an excellent solvent for many organic and inorganic substances, and is widely used in various industries. It can be used as a solubilizer for some substances with low solubility in water, for example, as a solvent and solubilizer for dyestuffs in the fiber industry, and as a solvent in the synthesis of antimicrobial agents such as chloramphenicol. Acetamide is slightly alkaline and can be used as an antacid for varnish, explosives and cosmetics. Acetamide is hygroscopic and can be used as a wetting agent for dyeing; it can also be used as a plasticizer for plastics. Acetamide chlorination or bromination produces N-halogenated acetamide, which is a halogenated reagent for organic synthesis. Acetamide is also a raw material for the manufacture of drugs and fungicides. Acetamide is an antidote for the poisoning of fluoroacetamide, an organofluorine insecticide. The mechanism of action is that the chemical structure of the product is similar to that of fluoroacetamide, which can compete with acetamidase, so that fluoroacetamide does not produce fluoroacetic acid, eliminating the toxic effect of the latter on the tricarboxylic acid cycle and achieving the purpose of detoxification.

Storage Methods
Store in a sealed and dry place.
The product is packed in iron drums of 180kg each. store in a cool, ventilated and dry place, avoid sunlight, not close to fire sources, pay attention to light handling, and transport according to the regulations of toxic substances.