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Factory Cheap Medical Biotechnology - China Doxifluridine Manufacture Supplier – Longo Detail:
Structural Formula
Physical
Appearance：white Solid
Density：1.3751 (estimate)
Melting Point：188-192 °c(lit.)
Specific Rotation ：d25 +18.4° (c = 0.419 In Water)
Refractivity：20 °(c=1, H2o)
Storage Condition ：inert Atmosphere,room Temperature
Acidity Factor(pka)：7.4(at 25℃)
Safety Data
Hazard category：Not dangerous goods
Dangerous goods transport no：
Packaging category：
Application
1. As a prodrug of 5-Flurouridine. A fluorinated pyrimidine nucleoside with cytostatic activity. Clinically used for gastric cancer, colorectal cancer, breast cancer, the remission rate can reach more than 30%
2. As a intermediate for Fluorouracil antitumor drugs
Introduction to uses
1. Fluorouracil-based antitumour agents are precursors to fluorouracil. The enzyme thymidine phosphorylase, which is present in tumour tissue, acts on it to convert it into fluorouracil in the tumour, thus exerting an anti-tumour effect. It has a strong anti-tumour specificity and low toxicity. It is clinically used in gastric cancer, colorectal cancer and breast cancer, with remission rate up to 30% or more.
2. Pharmaceutical intermediate.
3. It is an antitumour agent, a precursor drug of fluorouracil (5-FU), which is converted into free fluorouracil by the action of pyrimidine nucleoside phosphorylase in tumour tissues, thus inhibiting the biosynthesis of DNA and RNA in tumour cells and showing its antitumour effect. Since the activity of this enzyme is higher in tumour tissues than in normal tissues, the conversion of 5-FU into 5-FU in tumour tissues is rapid and selective for tumours. It is used in the treatment of breast, stomach and rectal cancers and has low toxicity.
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With state-of-the-art technologies and facilities, strict good quality regulate, reasonable cost, exceptional assistance and close co-operation with prospects, we're devoted to supplying the good benefit for our customers for Factory Cheap Medical Biotechnology - China Doxifluridine Manufacture Supplier – Longo , The product will supply to all over the world, such as: Nairobi, El Salvador, Guyana, We taking advantage of experience workmanship, scientific administration and advanced equipment, ensure the product quality of production, we not only win the customers' faith, but also build up our brand. Today, our team is committed to innovation, and enlightenment and fusion with constant practice and outstanding wisdom and philosophy, we cater to the market demand for high-end products, to do professional products.
By Heather from Spain - 2017.07.28 15:46
This is a very professional wholesaler, we always come to their company for procurement, good quality and cheap.
By Deirdre from Argentina - 2018.06.18 17:25
