Structural Formula
Physical
Appearance:white Crystalline Powder
Colour:white To Almost White
Density:1.3129 (rough Estimate)
Melting Point:186-188 °c(lit.)
Boiling Point:385.05°c (rough Estimate)
Refractivity:33 °(c=1, 1mol/l Naoh)
Specific Rotation:18.6 º(c=3, H2o)
Storage Condition:2-8°c
Acidity Factor(pka):pk1:9.79;pk2:12.85 (25°c)
Spinability:α]20/d +19±1°, C = 1% In H2o
Solubility In Water:soluble
Stability:stable. Incompatible With Strong Oxidizing Agents
Safety Data
Hazard category:Not dangerous goods
Dangerous goods transport no:
Packaging category:
Application
1.Used as a pharmaceutical intermediate for the synthesis of antiviral and anti-HIV drugs.
2.As an intermediate of Zivdodine
Uses:
Thymidine is a deoxyribonucleoside containing a thymine base. Thymidine is a nucleoside formed by linking thymidine to D-ribose through a β-glycosidic bond. Thymidine is used in the preparation of anti-AIDS drugs (e.g. zidofuridine, stavudine) and in the synthesis of antiviral drugs. It can also be used as a pharmaceutical intermediate and exported directly.
Bioactivity:
Thymidine(Deoxythymidine,2'-Deoxythymidine,5-Methyldeoxyuridine,DThChemicalbookyd,NSC21548) is a pyrimidine nucleoside consisting of thymine, a pyrimidine base attached to the sugar deoxyribose. As a component of DNA, thymine nucleosides pair with adenine in the DNA double helix.