Structural Formula
Physical
Appearance: white crystalline powder
Density.
Melting point: 259-268°C (dec.)
Boiling point.
Refractivity
Flash point.
Safety Data
Hazardous category.
Dangerous Goods Transport Number.
Packing category.
Application
Citicoline is available as a supplement in over 70 countries under a variety of brand names: Cebroton, Ceraxon, Cidilin, Citifar, Cognizin, Difosfocin, Hipercol, NeurAxon, Nicholin, Sinkron, Somazina, Synapsine, Startonyl, Trausan, Xerenoos, etc. When taken as a supplement, citicoline is hydrolyzed into choline and cytidine in the intestine. Once these cross the blood–brain barrier it is reformed into citicoline by the rate-limiting enzyme in phosphatidylcholine synthesis, CTP-phosphocholine cytidylyltransferase.
Sodium cytarabine is an organic substance with the chemical formula C14H25N4NaO11P2, a white crystalline powder.
It can gradually restore the function of limbs in hemiplegia caused by stroke, and can also be used for functional and consciousness disorders caused by other acute injuries to the central nervous system, and also for ischemic cerebrovascular disease and vascular dementia.
Pharmacological effects
Promotes cerebral substance metabolism and improves cerebral circulation by decreasing cerebrovascular resistance and increasing cerebral blood flow. It also enhances the function of the brainstem upward reticular activation system, strengthens the function of the vertebral system and improves motor paralysis, so it has a certain effect on promoting the recovery of brain function and promoting awakening. After injecting cytophosphorus choline sodium injection, it can rapidly enter the blood, and some of it can enter the brain tissue through the blood-brain barrier. The choline part becomes a good methylation donor in the body and can have transmethylation effect on many compounds, and about 1% of choline is excreted from urine.