Structural Formula

Physical

Appearance: light yellow to colorless transparent liquid
Density: 0.993 g/mL at 25 °C(lit.)
Melting point: 7.2 °C
Boiling point: 238-239 °C(lit.)
refractivity: n20/D 1.528(lit.)
Flash point: 229 °F

Safety Data
general

Application
4′-Methylpropiophenone is a chemical reagent used in electrocarboxylation reactions. It is as a raw material for organic synthesis of agrochemicals, pharmaceuticals and dyestuff.

4-Methylpropiophenone is a chemical reagent with an aromatic ketone that is propiophenone bearing a methyl group at C-4. It serves as pharmaceutical and synthesis material intermediate, and it is also used in electrocarboxylation reactions.
Solubility: Soluble in chloroform and hexane.
Notes：Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Application p-Methylpropiophenone is an intermediate of the pharmaceutical drug Brain Pulsatilla, which can be used as an organic synthesis intermediate and pharmaceutical intermediate, mainly in laboratory research and development processes and in chemical production processes. The synthesis was carried out using a chiral adsorption inducer, alkaloids, to induce the immobilization of p-methylpropiophenone by carbon dioxide electrolysis of α-7,-α-hydroxy-4-methyl-phenylacetic acid. It was found that 37.39% yield and S-32.78% ee value were obtained by constant current electrolysis at a current density of 1,1 mA-Cm-2 at 0 °C with ring stainless steel as the cathode, magnesium rod as the sacrificial anode, tetrabutylammonium iodide as the electrolytic support salt and O.016 g cinchonine as the inducing agent.

Emergency response to a spill
1. Precautions for personnel, protective equipment and emergency procedures
Prevent inhalation of vapours, aerosols or gases.
2. Environmental precautions
Do not allow product to enter sewers.
3. Methods and materials for containment and removal of spillage
Store in suitable closed disposal containers.
Handling disposal and storage
1. Precautions for safe handling
General fire protection measures.
2. Conditions for safe storage, including any incompatibilities
Store in a cool place. Keep containers tightly closed and store in a dry and ventilated place.
Opened containers must be carefully resealed and kept in an upright position to prevent leakage.
Definition： 4-methylpropiophenone is an aromatic ketone that is propiophenone bearing a methyl group at C-4. It derives from a propiophenone.